Provisional Mortality Data – United States, 2020

April 8th, 2021|

The age-adjusted death rate increased by 15.9% in 2020. Overall death rates were highest among Black and American Indian or Alaska Native people. COVID-19 was the third leading cause of death, and the COVID-19 death rate was highest among Hispanics. ...

From Vaccine Nationalism to Vaccine Equity — Finding a Path Forward

April 8th, 2021|

The global effort to develop safe and effective Covid-19 vaccines has yielded remarkable results, owing in part to early, decisive investments in clinical discovery through efforts such as Operation Warp Speed. These achievements highlight the payoff of stable, long-term support of basic research… ...

Escaping Catch-22 — Overcoming Covid Vaccine Hesitancy

April 8th, 2021|

On September 8, 2020, AstraZeneca announced that it was pausing its late-phase SARS-CoV-2 vaccine trial because of a serious adverse event in a U.K. participant. The next day, my hairdresser, Ms. J. asked me what I thought about the news. I said the halting of the trial to investigate the adverse…...

Vancomycin Infusion Reaction — Moving beyond “Red Man Syndrome”

April 8th, 2021|

In 1959, an article entitled "An Anaphylactoid Reaction to Vancomycin" hypothesized that vancomycin-induced histamine release from mast cells had clinical manifestations similar to those of anaphylaxis but less severe. The author named this reaction "Red Man Syndrome," reflecting the diffuse… ...

Audio Interview: Antibody Responses to Natural Infection and Vaccination

April 8th, 2021|

The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission, diagnosis, and treatment of Covid-19 is the subject of ongoing updates from infectious disease experts at the Journal. In this audio interview conducted… ...

EARLY RELEASE: Factors Associated with Participation in Elementary School-Based SARS-CoV-2 Testing – Salt Lake County, Utah, December 2020-January 2021

April 7th, 2021|

Investigators analyzed data on in-school COVID-19 testing among 594 students who were exposed to 33 index patients at 13 elementary schools. Compared with non-Hispanic White students, participation in the program was higher among students identifying as Hispanic/Latino White or members of another racial minority group. ...

COVID-19: WHO chief outlines five ‘vital changes’ to address inequities

April 7th, 2021|

Investing in equitable production and access to COVID-19 vaccines, tests and treatments, is among five “vital changes” the world needs to make this year to address the inequalities the pandemic has exacerbated, the UN’s top health official said, marking World Health Day on Wednesday.  ...