The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission, diagnosis, and treatment of Covid-19 is the subject of ongoing updates from infectious disease experts at the Journal. In this audio interview conducted… ...
The dramatic saga of the acquired immunodeficiency syndrome (AIDS) features an early sense of helplessness and frustration in the face of a mysterious new disease, courage on the part of the afflicted, and the gradual accrual of groundbreaking scientific advances that have brought hope to a… ...
The World Health Organization (WHO) recommends 3 days of oral amoxicillin (80 mg per kilogram of body weight per day) in children younger than 5 years of age who have fast-breathing pneumonia (cough lasting Journal, two well-performed randomized, controlled trials challenge these recommendations in… ...
To the Editor: We report a case of variant Creutzfeldt–Jakob disease (CJD) that was plausibly related to accidental occupational exposure in a technician who had handled murine samples contaminated with the agent that causes bovine spongiform encephalopathy (BSE) 7.5 years earlier. In May 2010,… ...
Each year, approximately 920,000 children die from pneumonia before the age of 5 years. Providing greater access to appropriate and effective treatment is an important goal. Treatment of bacterial pneumonia requires an effective antibiotic agent administered in adequate doses for an appropriate… ...
To the Editor: To address the coronavirus (Covid-19) pandemic, strict social containment measures have been adopted worldwide, and health care systems have been reorganized to cope with the enormous increase in the numbers of acutely ill patients. During this same period, some changes in the… ...
It’s a sunny Sunday in San Francisco as I tackle overdue clinic notes and Covid-19 sweeps the planet. I am scheduled to speak in 10 other states over the coming weeks, and as a healthy, middle-aged physician from a region with growing numbers of infections, I’m as likely to be a...
In 2015, acute lower respiratory tract infections caused 7.4 deaths per 1000 live births (95% confidence interval [CI], 6.7 to 8.8) worldwide. These infections disproportionately affected children in impoverished areas. The epidemiologic characteristics of pneumonia are changing rapidly as a result… ...
"Try Googling ‘record-setting lake trout New Hampshire,’" I found myself saying recently to an anxious patient while we explored ways to cope with the Covid-19 pandemic. He loves fishing, and I remembered a story in the paper recently — just barely pre-plague — that showed a smiling sportsman… ...
To the Editor: Data on Covid-19 in patients with immune-mediated inflammatory disease who have received anticytokine biologics, other immunomodulatory therapies, or both on a long-term basis are scarce. Trials to assess the efficacy of antirheumatic therapies such as hydroxychloroquine and… ...
